Monster at the Door? Seed of the Next Pandemic? (Image from Flickr, by Olaf) |
Flu season
is quickly approaching and, as usual, only a small fraction of Americans will
get vaccinated. Yet seasonal influenza continues to be one of the deadliest
diseases in the world, killing an average of 35,000 people per year in the U.S.
alone, while every 20-40 years, a particularly deadly new pandemic variety of
influenza evolves killing far more than this. The 1918 pandemic was the worst,
with worldwide mortality estimated at 50 million.
A similar
deadly outbreak could happen again at any time and scientists predict that such
an outbreak is inevitable. Some
believe it could be far worse than in 1918, as it is much easier to travel
long distances to spread the disease and there are far more large crowded slums
in which germs can easily spread from person to person and far more
malnourished individuals with weakened immune systems. There are also more
people selling and buying at “wet
markets” where highly infectious avian strains of influenza sometime
proliferate. Furthermore, there are several deadly avian strains still
circulating among wild birds for which we have little or no immunity. Scientists
have recently shown that it would only take a few random mutations to make one
of these strains (H5N1) easily transmissible between people.
With
seasonal flu, the majority of deaths occur among the elderly, infants and
immune-compromised (including the malnourished). However, even for the majority
of those who get the disease and survive, the consequences are serious,
including costly hospital and doctor’s visits, lost income and missed school
days. It is estimated that the U.S. alone loses $10 billion per year due to
influenza.
There is no
reason why so many people must die from this disease or even be sickened from
it. Contrary to the delusions of the
anti-vaccination movement, seasonal flu vaccines are generally quite
effective, especially when 70-80% of community members are vaccinated, as this
leads to “herd” immunity which protects those who have not been vaccinated as
well as those who received the vaccine but still did not get immunity.
Furthermore, serious side effects from flu vaccines are rare, while mild side
effects are generally quite mild (e.g., soreness, headache, fever).
While the
oldest and youngest members of our society are the most vulnerable to influenza
deaths, school-age children continue to be the most fertile incubators of the
virus, spreading the germ at school and day care centers with their peers and
then bringing the germ home to share with their families and neighbors. Not
only do small children tend to put their fingers in their own (and each
other’s) noses, eyes and mouths more often than adults (and wash less frequently),
they are also “super-spreaders,” according to a recent piece in Scientific American, since they “shed” more virus
particles for longer periods of time than do adults.
Consequently,
the most effective way to protect seniors, as well as the rest of us, is to
vaccinate children. According to the Scientific American article, studies
indicate that immunizing 20% of children in a community is more effective at
protecting seniors than immunizing 90% of the seniors, while immunizing 70% of
schoolchildren may protect everyone in the community (including the elderly).
There is
actually hard evidence for this. One of the last deadly flu pandemics occurred
in 1957 (there was another deadly one in 1968 that killed 500,000 worldwide).
In response, the Japanese launched a mandatory vaccination program for all
schoolchildren that lasted for the next ten years. During this time, excess
deaths from influenza and complications related to influenza fell by half. Once
the program ended, vaccination rates declined and death rates increased
significantly, Scientific American reports.
Requiring
mandatory flu vaccines is not likely to happen in the U.S., even though other
vaccinations (e.g., measles, mumps, polio) are
required before kids can go to school and despite the fact that so many lives
could be saved by initiating such a program. Anti-vaccination propaganda and
misinformation continue to fuel a hysteria that has resulted in a powerful
lobby against vaccinations. Furthermore, flu vaccines must be reconfigured each
year, which means that, unlike polio and measles vaccines, one must receive a
new flu inoculation each year. Lastly, only a couple of companies are currently
producing flu vaccines in the U.S. and few are willing to start because of
fears of liability and profitability (they must produce the vaccine well in
advance of flu season based on scientific predictions and models and then hope
that enough consumers will later purchase the vaccine).
Nevertheless,
sufficiently high immunization rates can be obtained through voluntary
community programs centered on schools, particularly with an effective outreach
program. Some schools already offer FluMist nasal spray free of charge to
students. In one district in Florida, vaccination rates have reached 65% as a
result of their free immunization program, while the incidence of influenza
over the last two years has been reduced to nearly zero. The consequences for
kids are far fewer absences and more time in school learning. For the rest of
us, it means fewer days lying in bed with fevers and chills, and fewer hospital
visits and deaths for our infants and grandparents.
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